Our first job is to listen to and observe what our customers need, and meet those needs with quality products and services. Chryseobacterium species are gramnegative bacillus widely distributed in nature. We present the clinical course of a 52yearold african male with a medical history of end stage renal disease esrd in hemodialysis with multiple episodes of. Antimicrobial susceptibility and epidemiology of a.
Clinical and microbiological characteristics of chryseobacterium. Understandably, an immunocompromised host may be affected by c. Chryseobacterium indologenes is an uncommon human pathogen that has been rarely reported in the literature as a cause of infection, but despite low virulence, this opportunistic bacteria is resistant to many antimicrobial agents. Routine haemogram showed leukocytosis with high erythrocyte. Reported infections include bacteremia, pneumonia, meningitis, myositis, keratitis, and indwelling devices. Chryseobacterium indologenes noncatheterrelated bacteremia.
Identification and virulence of chryseobacterium indologenes. Nursing homeassociated infections and antibiotic resistant pathogens constitute common and serious problems in the geriatric population. The patient was injured in a riding lawn mower accident that trapped him underwater in a pond. Chryseobacterium is a genus of gramnegative bacteria. Chryseobacterium indologenes is an uncommon human pathogen, but the incidence of bacteremia has been increasing with use of broadspectrum antimicrobial agents. Ventilatorassociated pneumonia caused by chryseobacterium. Treatment of chryseobacterium indologenes ventilator.
The api 20e test result gave the closest identification to chryseobacterium indologenes 86. The most active antimicrobials were the newer quinolones garenoxacin, gati. Herein, we report the first case in europe and the second case in an immunocompetent patient of peritoneal dialysisassociated c. Chryseobacterium indologenes is an uncommon human pathogen reported in hospital outbreaks in taiwan and there have been some sporadic cases reported in europe and in the usa mainly from immunesuppressed patients. Chryseobacterium indologenes, novel mannanaseproducing bacteria. Chryseobacterium form typical yelloworange color colonies due to flexirubintype pigment. Based on fatty acid methyl ester analysis, isolates were found to share similarities with c.
It is widely distributed in environmental sources including water, soil and plants omar et al. First isolation and characterization of chryseobacterium. Chryseobacterium indologenes previously classified as flavobacterium indologenes is a gram. Introduction we report the seventh case of chryseobacterium indologenes occurring in the united states of america. The highest chryseobacterium prevalence was detected among the elderly. Differences in clinical manifestations, antimicrobial susceptibility. Based on sequencing results of partial 16s rrna gene, isolates shared 99% identities e value 2e 50 with the 16s rrna sequence of c. We report a rare case of urinary tract infection by chryseobacterium indologenes in a young girl, operated for renal calculus and successfully treated with piperacillintazobactam combination.
Chryseobacterium indologenes is a gramnegative, aerobic, nonfermenting, nonmotile, catalase, oxidase, and indole positive bacillus. The genus contains more than 100 described species from diverse habitats, including freshwater sources, soil, marine. Although this bacterium only rarely causes human disease, it is sometimes found in food and water sources, usually in hospitals as a nosocomial transinfection. Chryseobacterium is a genus of bacteria in the family flavobacteriaceae. Severe sepsis due to chryseobacterium indologenes in an. Chryseobacterium indologenes in a woman with acute leukemia.
Chryseobacterium indologenes, formerly known as fla. Limited data are available on chryseobacterium spp. A 32yearold caucasian woman with metastatic breast cancer presented to a hospital emergency department with bilateral radiationinduced pleural. Urinary tract infection by chryseobacterium indologenes. Chryseobacterium indologenes infection in a newborn. Chryseobacterium indologenes pneumonia case presentation 1. Chryseobacterium indologenes and chryseobacterium gleum are human pathogens and are former members of the genus flavobacterium vandamme et al. Peritonitis remains an important complication of peritoneal dialysis. Chryseobacterium indologenes peritonitis in a peritoneal. A cluster of chryseobacterium indologenes cases related to drainage water in intensive care units volume 39 issue 8 mireia cantero, lina m. Pdf chryseobacterium indologenes is an uncommon human pathogen. Fifty isolates 24 chryseobacterium meningosepticum, 20 chryseobacterium indologenes, two chryseobacterium gleum, and 4 chryseobacterium.
P r hsueh, l j teng, s w ho, w c hsieh, and k t luh department of laboratory medicine, national taiwan university hospital, taipei, republic of china. The genus contains more than 100 described species from diverse habitats, including freshwater sources, soil, marine fish, and human hosts. Chryseobacterium indologenes, a possible emergent organism. Chryseobacterium indologenes is a gramnegative and nonmotile bacteria from the genus of chryseobacterium which has been isolated from a human. Chryseobacterium indologenes is a nonfermantative yellowpigmented gramnegative bacillus and is widely distributed in nature. Ccug 52546t, chryseobacterium indologenes lmg 8337t, chryseobacterium gleum ccug 14555t, chryseobacterium jejuense js178t, chryseobacterium oranimense h8t and chryseobacterium joostei lmg 18212t were used as reference strains for this study. Most infections have been detected in hospitalized patients with severe underlying. This case report describes a 42yearold woman of wolofa ethnicity who was. Clinical and microbiological characteristics of chryseobacterium indologenes bacteremia. Typically thought of as an organism of low virulence, it may cause serious infections, particularly among the immunocompromised. The newly classified and renamed elizabethkingia, chryseobacterium and myroides genera were originally included among the different species that belong to the genus flavobacterium. Members the genus chryseobacterium are widely distributed microorganisms that can be recovered from a wide variety of environments, such as fresh water, sewage and wastewater, soil or food sources, such as milk, poultry and meat and dairy products.
The aim of the present study was to isolate a novel and potential pectinase producing bacterium as well as optimization of its various parameters for maximum enzyme production. There are approximately 80 species of chryseobacterium, most of which are nonpathogenic environmental isolates, usually associated with moist environments. Evaluation of treatment outcomes for chryseobacterium. The patient was injured in a riding lawn mower accident that trapped him. Chryseobacterium indologenes in a woman with metastatic breast cancer in the. The most active antimicrobials were the newer quinolones garenoxacin, gatifloxacin, and levofloxacin, each. All isolates of c indologenes, flavobacterium indologenes, or flavobacterium aureum. Chryseobacterium indologenes are the two species generally isolated from clinical specimens. The gramnegative bacillus chryseobacterium indologenes causes infection mostly in immunocompromised patients with severe underlying disease, mainly in asia. There have been an increasing number of infections in fish associated with different species of chryseobacterium, being considered potentially emerging pathogens.
The patient was successfully treated with piperacillintazobactam. Unforeseeable presentation of chryseobacterium indologenes infection in a. A cluster of chryseobacterium indologenes cases related to. We present a case of ventilatorassociated pneumonia caused by c. After short stay in er she had being unstable and transferred to the icu. The correlation between colistin, tigecycline, and daptomycin consumption and prevalence of chryseobacterium indologenes. Chryseobacterium indologenes is a nonlactosefermenting, gramnegative, health careassociated pathogen hcap. Elizabethkingia, chryseobacterium and myroides species. This report describes a 66yearold critically ill trauma patient who developed vap, which was caused by c indologenes. Chryseobacterium indologenes are aerobic, gram negative, nonfermentative rods that are intrinsically multidrug resistant. Chryseobacteria are not a part of the human flora but are found in soil, plants, and foodstuffs.
Chryseobacterium indologenes is a pathogen of american bullfrogs lithobates catesbeianus and humans. Jul 26, 20 we report the seventh case of chryseobacterium indologenes occurring in the united states of america. Presently, most of the pectinases are of plant origin but there are only a few reports on bacterial pectinases. Chryseobacterium indologenes pneumonia case presentation. Chryseobacterium indologenes an overview sciencedirect topics. A 32yearold caucasian woman with metastatic breast cancer presented to a hospital emergency department with bilateral radiationinduced pleural effusions and. Chryseobacterium indologenes pneumonia in a patient with. The genus flavobacterium was created in 1923 for a group of nonspore forming, aerobic gram negative rods, with the ability to produce yellow pigmented colonies. It is a rare human pathogen that has been isolated from water systems and humid surfaces of the hospital environment. We investigated clinical characteristics and treatment outcomes for c.
Fifty isolates 24 chryseobacterium meningosepticum, 20 chryseobacterium indologenes, two chryseobacterium gleum, and 4 chryseobacterium spp. It is possible that physicians may encounter this pathogenic microorganism in hospital environment such as mechanical ventilator circuits. Chryseobacterium indologenes pneumonia in a patient with non. Cureus chryseobacterium indologenes, an emerging bacteria. This case, affecting a fit and well adventure traveler, demonstrates that it may be an agent of severe sepsis in otherwise healthy humans. Unforeseeable presentation of chryseobacterium indologenes. A case of noncatheterrelated bacteremia caused by chryseobacterium indologenes in a nonneutropenic man with a solid tumor is described. Chryseobacterium and elizabethkingia species may be long, thin, slightly curved, and occasionally filamentous on gram stain.
Pdf chryseobacterium indologenes pneumonia in a patient with nonhodgkins lymphoma. In patients with c indologenes bacteremia, there was no documented infective figure 1. Recurrent port infection due to chryseobacterium indologenes ncbi. Ht4b 16s ribosomal rna gene partial sequence ln624801. Chryseobacterium indologenes is an environmental organism which is usually an opportunistic pathogen, most usually associated with nosocomial or devicerelated infections. With 215 c indologenes isolates between january 1, 2004 and september 30, 2011, at a medical center, we analyzed the relationship between the prevalence of c indologenes infections and total prescription of colistin and tigecycline, clinical manifestation, antibiotic susceptibility, and outcomes.
Chryseobacterium indologenes is an uncommon human pathogen. Atcc stands ready to support our customers needs during the coronavirus pandemic. Chryseobacterium indologenes, formerly known as flavobacterium indologenes or flavobacterium aureum belongs to cdc group iib. We report the case of a catheterrelated bloodstream infection caused by chryseobacterium indologenes, an uncommon. It is ubiquitous and intrinsically resistant to several antibiotics. Pdf chryseobacterium indologenes, a possible emergent. Chryseobacterium indologenes, a possible emergent organism resistant to carbapenem antimicrobials after stem cell transplantation.
Chryseobacterium indologenes, a nonmotile gramnegative rod, though widely distributed in nature, is an uncommon human pathogen. Pdf on jan 1, 2018, danny alon and others published. We report the seventh case of chryseobacterium indologenes occurring in the united states of america. Jiunnong lin,a,b,c chunghsu lai,a,c chihhui yang,d yihan huanga. Chryseobacterium indolgenes in septicemia a rare case report. Chryseobacterium indologenes is nonmotile, oxidase, and indole positive gramnegative. Urinary infection due to chryseobacterium indologenes nefrologia. Chryseobacterium indologenes, formerly known as flavobacterium indologenes. To report a case of chryseobacterium indologenes ventilatorassociated pneumonia vap in a critically ill trauma patient. Urine culture was performed and an increase of 100,000cfuml of esbl carrying escherichia coli and chryseobacterium indologenes are found. Although chryseobacterium indologenes is the most common human isolate within this group, recovery of the organism is not always associated with infection. Although chryseobacterium meningosepticum is the most pathogenic member of the genus, c. Nevertheless the knowledge of the diversity of species associated with fish disease is partial due to the problems for a correct identification at the species level based exclusively on phenotypic laboratory methods. Pectinase is one of the important enzymes of industrial sectors.
May 30, 2015 chryseobacterium indologenes pneumonia case presentation 1. The golden death bacillus chryseobacterium nematophagum is. Chryseobacterium meningosepticum flavobacterium meningosepticum. Chryseobacterium species are chemoorganotrophic, rod shape gramnegative bacteria.
Clinical and microbiological characteristics of flavobacterium indologenes infections associated with indwelling devices. Formerly flavobacterium indologenes, chryserobacterium indologenes is a yellow pigmented, gramnegative filamentous, nonmotile rod and can be found in soil, plants, foodstuffs and water sources including those found in hospitals 1234. Chryseobacterium indologenes, a nonfermentative gramnegative bacilli distributed widely in nature, is an emerging nosocomial pathogen, inherently resistant to a wide. Clinical and epidemiological features of chryseobacterium. Confirmation of genus designation was obtained following wholegenome sequencing of the 4. Reports detailing bacteremia caused by chryseobacterium indologenes remain limited, with most cases reported.
Jan 14, 2011 chryseobacterium indologenes is an uncommon human pathogen. Chryseobacterium indologenes in a woman with metastatic breast cancer in the united states of america. Role of chryseobacterium indologenes infection in a female. We report a rare case of chryseobacterium bacteremia in an endstage renal disease nursing home resident, that was diagnosed using multiplex pcr and was successfully treated with intravenous. Pages in category chryseobacterium the following 10 pages are in this category, out of 10 total. Most infections have been detected in hospitalized patients with severe underlying diseases who had indwelling devices implanted. A threemonthold female infant born at term by caesarean section with meningomyelocele and congenital diaphragmatic hernia had two surgeries for the repair of meningomyelocele and diaphragmatic hernia on her. Chryseobacterium indologenes an overview sciencedirect. Respiratory system examination was suggestive of leftsided pneumonia with pleural effusion.
A 42yearold man diagnosed with gastric nonhodgkins lymphoma 2 years earlier, for which he had undergone treatment, presented with expectorative cough, exertional shortness of breath and leftsided chest pain of 3 months duration. Chryseobacterium indologenes, a nonfermentative gram negative bacillus, is an uncommon pathogen in humans. The isolates were negative for the gramreaction, nonmotile, rodshaped and catalase and. Chryseobacterium gleum and chryseobacterium indologenes. Chryseobacterium indologenes keratitisa case report. Emerging chryseobacterium indologenes infection in indian. It causes a variety of invasive infections especially in hospitalized patients with severe underlying disease and with indwelling devices. Pdf chryseobacterium indologenes infection in a newborn. Some species of chryseobacterium have been involved in human infections, acting as sporadic but severe opportunistic nosocomial pathogens. Eight bacterial strains isolated from diseased rainbow trout n55 and atlantic salmon n53 were characterized by phenotypic and molecular taxonomic methods. Chryseobacterium species are rare human pathogens that are found in the environment and cause a variety of infections, usually in patients with altered. Chryseobacterium indologenes bacteremia in an infant core. Chryseobacterium indologenes species was primarily isolated in 1993 from the tracheal aspirate of a patient with ventilatorassociated pneumonia 4. Introduction chryseobacterium indologenes is an uncommon human pathogen.
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